The genus Anthemis L. belongs to the family Asteraceae, is the second largest genus in the Compositae family, tribe Anthemideae, about 130 species of genus Anthemis occur throughout the world consists of 39 annual and perennial species distributed all over of Iran. According to literature, this species was not the subject of research up to nowtherefore its chemical composition is not well known. In this research three samples of Anthemis coelopoda . were collected from Gilan province, in the 2020. specimen is deposited in Central H and analyzed by GC and GC/MS. Main components from sample one Gilan: Loshan, before Hanifa Imamlower were β- calacorene 35.9%, Elemicin 24.0% and n-dodecanol 8.8% and in leaf were β- calacorene 26.8%, elemicin 13.9% and n-dodecanol 11.8%, and essential oil yield from flower were 0.04% and leaf were 0.03%. Main components from sample two Gilan: southwest of Rudbar, Lake 1181 meters high, in flower were γ- cuprenene 18.2%, n-dodecanol 13.8% and geranyl propanoate 7.4% and in leaf were n-dodecanol 13.5%, - terpinen-7-al 10.8% and geranyl propanoate 10.2%, and essential oil yield from flower were 0.10% and in lead were 0.07%. Main components from sample thee Gilan: Loshan, before Hanifa Imamzadeh, near the cement mine, 801 meters high, in flower were n-dodecanol 11.8%, - terpinen-7-al 9.3% and Cumin aldehyde 8.8% and in leaf were n-dodecanol 14.9%, - terpinen-7-al 11.1% and 5-hydroxy isobornyl isobutanoate 10%, and essential oil yeild from flower were 0.09% and in leaf were 0.06%. Sampling simultaneously on one day from three different areas (Samples 1 and 3 were collected from one area but at a great distance) their essential oils were examined for chemical composition and the results indicate different combinations and amounts in a species. This difference can be the result of differences in soil type and different plant water uptake.